Details subject to change
| DAY 1 | Friday, May 5, 2023 | |
| 7:00 am | Continental Breakfast |
| 7:50 – 8:00 am | Welcome |
| 8:00 – 8:30 am | Opening Address Integrating Precision Medicine into Cancer Care Promise and Progress Stephen Gruber, MD, PhD, MPH (City of Hope) |
| Precision Medicine in Cancer Care: Enterprise-wide Solutions | |
| 8:30 – 9:00 am | Keynote: Diagnostic Yield and Research Insights from the MSK-IMPACT Initiative Zsofia Stadler, MD (Memorial Sloan Kettering Cancer Center) |
| 9:00 – 9:20 am | Germline Genetic Testing Across a National Network: The Mayo Experience Niloy Jewel Samadder, MD (Mayo Clinic) |
| 9:20 – 9:40 am | Ethical Considerations for Scaled-up Approaches to Genetic Testing in Oncology Care Leila Jamal, ScM PhD, CGC (National Cancer Institute) |
| 9:40 – 9:55 am | Panel Discussion/Q&A |
| 9:55 – 10:15 am | 20-Minute Break |
| Bringing Cancer Genomics to the Community | |
| 10:15 – 10:35 am | Bringing Prostate Cancer Risk Assessment to the Community: A GENTleMEN’s PROMISE Heather Cheng, MD, PhD (University of Washington) |
| 10:35 – 10:55 am | Embedding Genetic Counselors in Gynecology Clinics Improves Uptake of Genetic Testing Alexi Wright, MD, MPH (Dana-Farber Cancer Institute) |
| 10:55 – 11:15 am | Embedded In-Clinic Genetic Testing Station to Optimize Germline Testing for Patients with Pancreatic Cancer Amie Blanco, MS, CGC (University of California San Francisco) |
| 11:15 – 11:30 am | Panel Discussion/Q&A |
| 11:30 – 11:50 am | 20-Minute Break |
| 11:50 am – 12:50 pm | Case Presentation Workshop - Clinical Challenges: Germline and Somatic Testing Moderated by Bita Nehoray, MS, CGC, and Elyssa Zukin, MS, CGC (City of Hope) |
| 12:50 – 1:50 pm | Lunch - EXACT Sciences sponsored session Tumor Genomics in Early and Advanced Breast Cancer |
| Hereditary Breast/Ovarian Cancer: Insights and Updates | |
| 1:50 – 2:20 pm | Keynote: Risk Management for High and Moderate Risk Gene Carriers: Are We Overtreating Patients? Allison Kurian, MD, MSc (Stanford University) |
| 2:20 – 2:40 pm | Mechanisms of Tumor Development in LFS Spectrum Breast Cancer Kara Maxwell, MD, PhD (University of Pennsylvania) |
| 2:40 – 3:00 pm | Improving Access to Genetic Testing and Clinical Management for HBOC in Underserved Populations Joanne Mortimer, MD (City of Hope) |
| 3:00 – 3:20 pm | Abbreviated and UltraFast Breast MRI for Intensive Surveillance in High-Risk Patients: Are we there yet? Olufunmilayo I. Olopade, MD, FACP (University of Chicago) |
| 3:20 – 3:35 pm | Panel Discussion/Q&A |
| 3:35 – 3:55 pm | 20-Minute Break |
| 3:55 – 4:55 pm | Case Presentation Workshop – HBOC, Moderate Risk, Risk Management Moderated by Susan Shehayeb, MS, CGC, and Elise Sobotka, MS, MPH, CGC (City of Hope) |
| 4:55 pm | Conference Day 1 Adjourn |
| 5:00 – 7:00 pm | Poster Session & Welcome Reception |
| DAY 2 | Saturday, May 6, 2023 | |
| 7:00 am | Continental Breakfast - CancerIQ sponsored session Making Precision Prevention Actionable and Equitable at Scale: CancerIQ Unveils New Offerings |
| 7:50 – 8:00 am | Welcome/Announcements |
| Precision Medicine: Therapeutics & Insights | |
| 8:00 – 8:30 am | Keynote: The Role of Germline Genetic Testing and Targeting Therapies for Pancreatic Cancer Vincent Chung, MD (City of Hope) |
| 8:30 – 8:50 am | Determining the Clinical Impact of Universal Genetic Testing Stacy Gray, MD, AM (City of Hope) |
| 8:50 – 9:10 am | Targets and Trials: Paired Tumor/Normal Testing for Clinical Trials Miguel Villalona-Calero, MD (City of Hope) |
| 9:10 – 9:30 am | Therapeutics and Insights from a Precision Oncology Tumor Board at Scale Kevin McDonnell, MD, PhD (City of Hope) |
| 9:30 – 9:50 am | From Genomics to Therapeutics for Lung Cancer: A Framework for Community Practice Integration Ravi Salgia, MD (City of Hope) |
| 9:50 – 10:05 am | Panel Discussion/Q&A |
| 10:05 – 10:25 am | 20-Minute Break |
| Hereditary Gastrointestinal Syndromes: Insights and Updates (Sponsored by the City of Hope Lynch Syndrome Center of Excellence) |
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| 10:25 – 10:55 am | Keynote: Lynch and Lynch-like Syndrome Heather Hampel, MS, CGC (City of Hope) |
| 10:55 – 11:15 am | Polyposis of Hereditary and Unknown Etiology: Who and How to Screen Carol Burke, MD, FACG, FASGE, FACP (Cleveland Clinic) |
| 11:15 – 11:35 am | Increasing Access to Cancer Genetics for Inherited Gastrointestinal Cancers: Update on the PREMM model Sapna Syngal, MD, MPH (Dana-Farber Cancer Institute) |
| 11:35 – 11:55 am | Vaccine Trials for Lynch Syndrome Eduardo Vilar-Sanchez, MD, PhD (MD Anderson Cancer Center) |
| 11:55 am – 12:15 pm | PRECEDE Update Gregory Idos, MD, MS (City of Hope) |
| 12:15 – 12:30 pm | Panel Discussion/Q&A |
| 12:30 – 1:30 pm | Lunch - AstraZeneca sponsored session Homologous Recombination Deficiency in Advanced Ovarian Cancer |
| 1:30 – 2:30 pm | Promoting Cancer Genomics Awareness, Knowledge and Connections through Social Media: Clinician & Patient Panel Dena Goldberg, MS, CGC (Dena DNA, Inc.); Clinician & Patient Panel: Alexea M. Gaffney-Adams, MD (Stony Brook Medical Associates); Allison Rosen, MS; Paige More (The Breasties) |
| Addressing Inequities in High-Risk Patient Care | |
| 2:30 – 3:00 pm | Keynote: Towards Equitable Access to Cancer Genetic Counseling for Diverse Public Hospital Patients: A Comparison of 3 Counseling Modes Rena Pasick, DrPH (University of California San Francisco) |
| 3:00 – 3:20 pm | Challenges and Approaches to High-Risk Management for Transgender Patients Iris Romero, MD, MS (University of Chicago) |
| 3:20 – 3:40 pm | Hereditary Cancer: Access and Care in Latinx Populations Yanin Chavarri-Guerra, MD, MSc (Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) |
| 3:40 – 4:00 pm | Medical Mistrust about Tumor Genomics Profiling among Black and African American Cancer Patients Michael Hall, MD, MS (Fox Chase Cancer Center) |
| 4:00 – 4:15 pm | Panel Discussion/Q&A |
| 4:15 – 4:35 pm | 20-Minute Break |
| 4:35 – 5:55 pm | Case Presentation Workshop – Gastrointestinal, Inequities, Targeted Therapies Moderated by Lauren Gima, MS, CGC, and Sandra Dreike, MS, CGC (City of Hope) |
| 5:55 pm | Conference Day 2 Adjourns |
| 7:00 – 10:00 pm |
A Night in Hollywood
Dinner Gala Starview Ballroom – Sheraton Universal
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| DAY 3 | Sunday, May 7, 2023 | |
| 7:00 am | Sunday Breakfast - Invitae sponsored session Case closed or jury's out? Universal Testing for Colorectal Cancer |
| 7:50 – 8:00 am | Welcome/Announcements |
| Updates in Hematologic and Pediatric Cancer Syndromes | |
| 8:00 – 8:30 am | Keynote: Advances in Identifying, Managing and Treating Hereditary Hematologic Malignancies Jane Churpek, MD, MS (University of Wisconsin-Madison) |
| 8:30 – 8:50 am | Dyskeratosis Congenita and the Spectrum of Telomere Biology Disorders: Genetic Workup and Care Considerations Sharon Savage, MD (National Cancer Institute) |
| 8:50 – 9:10 am | Implications for Carriers of Recessive Traits: Fanconi Anemia Pathway Rachelle Manookian, MS, CGC (City of Hope) |
| 9:10 – 9:30 am | Psychosocial Impact of Li Fraumeni Syndrome in Teens/Adolescents Rowan Forbes Shepherd, PhD (National Cancer Institute) |
| 9:30 – 9:50 am | Li-Fraumeni Syndrome: Updates and Outcomes from the LiFT Up Study Bita Nehoray, MS, CGC (City of Hope) |
| 9:50 – 10:05 am | Panel Discussion/Q&A |
| 10:05 – 10:25 am | 20-Minute Break |
| Emerging Topics in Cancer Screening and Genetic Testing | |
| 10:25 – 10:45 am | Keynote: Circulating Tumor DNA for Multi-Cancer Early Detection and Guiding Therapy Cristian Tomasetti, PhD (Translational Genomics Research Institute, City of Hope) |
| 10:45 – 11:05 am | National Programs for Screening and Genetic Testing Gad Rennert, MD, PhD (Carmel Medical Center / Clalit National Israel Control Center) |
| 11:05 – 11:25 am | RNA Analysis for Variant Interpretation: Benefits, Limitations and Clinical Utility Padma Sheila Rajagopal, MD, MPH, MSc (National Cancer Institute) |
| 11:25 – 11:45 am | Utility of Polygenic Risk Scores in Cancer Risk Assessment: Are We There Yet? Colin Pritchard, MD, PhD (University of Washington) |
| 11:45 am – 12:05 pm | Panel Discussion/Q&A |
| 12:05 – 12:20 pm | Wrap-up/Closing Remarks – Recap and a Look at What’s Ahead Kathleen Blazer, EdD, MS, CGC (City of Hope), Stephen Gruber, MD, PhD, MPH (City of Hope), and Olufunmilayo I. Olopade, MD, FACP (University of Chicago) |