MAY 5 TO 7, 2023

Details subject to change

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DAY 1 | Friday, May 5, 2023
7:00 am Continental Breakfast
7:50 – 8:00 am Welcome
8:00 – 8:30 am Opening Address
Integrating Precision Medicine into Cancer Care Promise and Progress
Stephen Gruber, MD, PhD, MPH (City of Hope)
Precision Medicine in Cancer Care: Enterprise-wide Solutions
8:30 – 9:00 am Keynote: Diagnostic Yield and Research Insights from the MSK-IMPACT Initiative
Zsofia Stadler, MD (Memorial Sloan Kettering Cancer Center)
9:00 – 9:20 am Germline Genetic Testing Across a National Network: The Mayo Experience
Niloy Jewel Samadder, MD (Mayo Clinic)
9:20 – 9:40 am Ethical Considerations for Scaled-up Approaches to Genetic Testing in Oncology Care
Leila Jamal, ScM PhD, CGC (National Cancer Institute)
9:40 – 9:55 am Panel Discussion/Q&A
9:55 – 10:15 am 20-Minute Break
Bringing Cancer Genomics to the Community
10:15 – 10:35 am Bringing Prostate Cancer Risk Assessment to the Community: A GENTleMEN’s PROMISE
Heather Cheng, MD, PhD (University of Washington)
10:35 – 10:55 am Embedding Genetic Counselors in Gynecology Clinics Improves Uptake of Genetic Testing
Alexi Wright, MD, MPH (Dana-Farber Cancer Institute)
10:55 – 11:15 am Embedded In-Clinic Genetic Testing Station to Optimize Germline Testing for Patients with Pancreatic Cancer
Amie Blanco, MS, CGC (University of California San Francisco)
11:15 – 11:30 am Panel Discussion/Q&A
11:30 – 11:50 am 20-Minute Break
11:50 am – 12:50 pm Case Presentation Workshop - Clinical Challenges: Germline and Somatic Testing
Moderated by Bita Nehoray, MS, CGC, and Elyssa Zukin, MS, CGC (City of Hope)
12:50 – 1:50 pm Lunch - EXACT Sciences sponsored session
Tumor Genomics in Early and Advanced Breast Cancer
Hereditary Breast/Ovarian Cancer: Insights and Updates
1:50 – 2:20 pm Keynote: Risk Management for High and Moderate Risk Gene Carriers: Are We Overtreating Patients?
Allison Kurian, MD, MSc (Stanford University)
2:20 – 2:40 pm Mechanisms of Tumor Development in LFS Spectrum Breast Cancer
Kara Maxwell, MD, PhD (University of Pennsylvania)
2:40 – 3:00 pm Improving Access to Genetic Testing and Clinical Management for HBOC in Underserved Populations
Joanne Mortimer, MD (City of Hope)
3:00 – 3:20 pm Abbreviated and UltraFast Breast MRI for Intensive Surveillance in High-Risk Patients: Are we there yet?
Olufunmilayo I. Olopade, MD, FACP (University of Chicago)
3:20 – 3:35 pm Panel Discussion/Q&A
3:35 – 3:55 pm 20-Minute Break
3:55 – 4:55 pm Case Presentation Workshop – HBOC, Moderate Risk, Risk Management
Moderated by Susan Shehayeb, MS, CGC, and Elise Sobotka, MS, MPH, CGC (City of Hope)
4:55 pm Conference Day 1 Adjourn
5:00 – 7:00 pm Poster Session & Welcome Reception
DAY 2 | Saturday, May 6, 2023
7:00 am Continental Breakfast - CancerIQ sponsored session
Making Precision Prevention Actionable and Equitable at Scale: CancerIQ Unveils New Offerings
7:50 – 8:00 am Welcome/Announcements
Precision Medicine: Therapeutics & Insights
8:00 – 8:30 am Keynote: The Role of Germline Genetic Testing and Targeting Therapies
for Pancreatic Cancer
Vincent Chung, MD (City of Hope)
8:30 – 8:50 am Determining the Clinical Impact of Universal Genetic Testing
Stacy Gray, MD, AM (City of Hope)
8:50 – 9:10 am Targets and Trials: Paired Tumor/Normal Testing for Clinical Trials
Miguel Villalona-Calero, MD (City of Hope)
9:10 – 9:30 am Therapeutics and Insights from a Precision Oncology Tumor Board at Scale
Kevin McDonnell, MD, PhD (City of Hope)
9:30 – 9:50 am From Genomics to Therapeutics for Lung Cancer: A Framework for Community Practice Integration
Ravi Salgia, MD (City of Hope)
9:50 – 10:05 am Panel Discussion/Q&A
10:05 – 10:25 am 20-Minute Break
Hereditary Gastrointestinal Syndromes: Insights and Updates
(Sponsored by the City of Hope Lynch Syndrome Center of Excellence)
10:25 – 10:55 am Keynote: Lynch and Lynch-like Syndrome
Heather Hampel, MS, CGC (City of Hope)
10:55 – 11:15 am Polyposis of Hereditary and Unknown Etiology: Who and How to Screen
Carol Burke, MD, FACG, FASGE, FACP (Cleveland Clinic)
11:15 – 11:35 am Increasing Access to Cancer Genetics for Inherited Gastrointestinal Cancers: Update on the PREMM model
Sapna Syngal, MD, MPH (Dana-Farber Cancer Institute)
11:35 – 11:55 am Vaccine Trials for Lynch Syndrome
Eduardo Vilar-Sanchez, MD, PhD (MD Anderson Cancer Center)
11:55 am – 12:15 pm PRECEDE Update
Gregory Idos, MD, MS (City of Hope)
12:15 – 12:30 pm Panel Discussion/Q&A
12:30 – 1:30 pm Lunch - AstraZeneca sponsored session
Homologous Recombination Deficiency in Advanced Ovarian Cancer
1:30 – 2:30 pm Promoting Cancer Genomics Awareness, Knowledge and Connections through Social Media: Clinician & Patient Panel
Dena Goldberg, MS, CGC (Dena DNA, Inc.); Clinician & Patient Panel: Alexea M. Gaffney-Adams, MD (Stony Brook Medical Associates); Allison Rosen, MS; Paige More (The Breasties)
Addressing Inequities in High-Risk Patient Care
2:30 – 3:00 pm Keynote: Towards Equitable Access to Cancer Genetic Counseling for Diverse Public Hospital Patients: A Comparison of 3 Counseling Modes
Rena Pasick, DrPH (University of California San Francisco)
3:00 – 3:20 pm Challenges and Approaches to High-Risk Management for Transgender Patients
Iris Romero, MD, MS (University of Chicago)
3:20 – 3:40 pm Hereditary Cancer: Access and Care in Latinx Populations
Yanin Chavarri-Guerra, MD, MSc (Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán)
3:40 – 4:00 pm Medical Mistrust about Tumor Genomics Profiling among Black and African American Cancer Patients
Michael Hall, MD, MS (Fox Chase Cancer Center)
4:00 – 4:15 pm Panel Discussion/Q&A
4:15 – 4:35 pm 20-Minute Break
4:35 – 5:55 pm Case Presentation Workshop – Gastrointestinal, Inequities, Targeted Therapies
Moderated by Lauren Gima, MS, CGC, and Sandra Dreike, MS, CGC (City of Hope)
5:55 pm Conference Day 2 Adjourns
7:00 – 10:00 pm
A Night in Hollywood
Dinner Gala
Starview Ballroom – Sheraton Universal
DAY 3 | Sunday, May 7, 2023
7:00 am Sunday Breakfast - Invitae sponsored session
Case closed or jury's out? Universal Testing for Colorectal Cancer
7:50 – 8:00 am Welcome/Announcements
Updates in Hematologic and Pediatric Cancer Syndromes
8:00 – 8:30 am Keynote: Advances in Identifying, Managing and Treating Hereditary Hematologic Malignancies
Jane Churpek, MD, MS (University of Wisconsin-Madison)
8:30 – 8:50 am Dyskeratosis Congenita and the Spectrum of Telomere Biology Disorders: Genetic Workup and Care Considerations
Sharon Savage, MD (National Cancer Institute)
8:50 – 9:10 am Implications for Carriers of Recessive Traits: Fanconi Anemia Pathway
Rachelle Manookian, MS, CGC (City of Hope)
9:10 – 9:30 am Psychosocial Impact of Li Fraumeni Syndrome in Teens/Adolescents
Rowan Forbes Shepherd, PhD (National Cancer Institute)
9:30 – 9:50 am Li-Fraumeni Syndrome: Updates and Outcomes from the LiFT Up Study
Bita Nehoray, MS, CGC (City of Hope)
9:50 – 10:05 am Panel Discussion/Q&A
10:05 – 10:25 am 20-Minute Break
Emerging Topics in Cancer Screening and Genetic Testing
10:25 – 10:45 am Keynote: Circulating Tumor DNA for Multi-Cancer Early Detection and Guiding Therapy
Cristian Tomasetti, PhD (Translational Genomics Research Institute, City of Hope)
10:45 – 11:05 am National Programs for Screening and Genetic Testing
Gad Rennert, MD, PhD (Carmel Medical Center / Clalit National Israel Control Center)
11:05 – 11:25 am RNA Analysis for Variant Interpretation: Benefits, Limitations and Clinical Utility
Padma Sheila Rajagopal, MD, MPH, MSc (National Cancer Institute)
11:25 – 11:45 am Utility of Polygenic Risk Scores in Cancer Risk Assessment: Are We There Yet?
Colin Pritchard, MD, PhD (University of Washington)
11:45 am – 12:05 pm Panel Discussion/Q&A
12:05 – 12:20 pm Wrap-up/Closing Remarks – Recap and a Look at What’s Ahead
Kathleen Blazer, EdD, MS, CGC (City of Hope), Stephen Gruber, MD, PhD, MPH (City of Hope), and Olufunmilayo I. Olopade, MD, FACP (University of Chicago)